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Controlled Release formulations of anti-tubercular drugs


The subject matter relates to Microparticle-based drug delivery systems. More specifically, it relates to such drug delivery systems wherein the drug(s), preferably anti tubercular drugs are prepared in a Fixed Dose Combination in a manner to increase their bioavailability in the intestinal area by by-passing the gastric environment of the stomach. The present invention follows a novel approach by using pH sensitive polymers and specific targeting markers.

Status of Patent: Indian Patent Applied For

Assistance given by IIPRD

  • Conducted Commercial Evaluation of the Product/Patent
  • IIPRD Conducting Licensing Exercise for the Patent targetting Medium Sized companies in Anti-Tubercular Market.
  • Patent Being prosecuted Khurana & Khurana, Advocates and IP Attorneys

  • Tablets with Enhanced Dissolution Rate


    The present technology provides tablets with enhanced dissolution rate of sparingly soluble drugs leading to increased bioavailability. Grains of solid dispersion of the drug in water soluble carrier are formed/cemented into tablets in a manner similar to that of cube sugar. Solid dispersions of drugs in carriers of poor compressibility can be easily formed into tablets of any suitable shape/size by known cube sugar technology. Resulting tablets are not only readily dispersible owing to capillary action but also ensure rapid dissolution of poorly soluble drug because of solid dispersion. Simultaneous exploitation of well-known approaches- solid dispersion, capillary action, optional surfactant and optional size reduction in the proposed technique results in steep enhancement of dissolution rate without compromising with content uniformity.

    Status of Patent: Indian Patent Granted

    Assistance given by IIPRD

  • Conducted Commercial Evaluation of the Product/Patent
  • Patent Successfully Prosecuted till Grant Through Khurana & Khurana, Advocates and IP Attorneys

  • Pharmaceutical Nanoelastic Vesicular Systems


    The present invention relates to non-ionic surfactant based nanoelastic vesicular systems comprising fluconazole or its pharmaceutically acceptable salts, solvates, enantiomers, polymorphs or mixtures thereof, processes for preparing the same and methods of use and treatment.

    Status of Patent: Indian Patent Pending

    Assistance given by IIPRD

  • Conducted Commercial Evaluation of the Product/Patent
  • Complete Patent Protection Through Khurana & Khurana

  • Novel Controlled Release Tablet Of Poorly Soluble Drug


    The subject matter relates to a novel attempt by the inventors to a controlled release dosage form for a range of poorly soluble drugs, especially, Carvedilol. The dosage form of the present invention uses a novel combination of solubilizer and a hrdrophilic swellable polymer to create a better and efficient controlled release formulation for poorly soluble drugs.

    Status of Patent: Indian Patent Pending

    Assistance given by IIPRD

  • Conducted Commercial Evaluation of the Product/Patent

  • Nano-Technology Based Herbal Topical Formulations


    The patent pertains to the field of topical herbal formulations based on nano technology having therapeutic properties. The subjet matter relates to nano-emulsion based topical synergistic herbal formulations which are effective against acne and other skin disorder. More specifically, the present invention is concerned with the prophylactic and therapeutic topical treatment of skin disorders of all types of acne, eczema, psoriasis, aging, scaring and the like.

    Status of Patent: Worldwide Patent Pending

    Assistance given by IIPRD

  • Conducted Commercial Evaluation of the Product/Patent
  • Executing the complete Licensing Exercise Worldover by Identifying, Negotiating and Closing the deal with one or more Potential Licensees

  • Thrust and Torque Generator without Reaction Mass


    The Patent pertains to a device for generating Thrust and Torque in space at industrial and/or military and/or space temperature range from electric power without involving reaction mass. The device for generating torque and thrust from electric power comprises of a main shaft and a cone assembly, where the cone assembly is supported on the main shaft and comprises of a spin drive motor and a precession drive motor. The device further comprises of a plurality of magnetized gyro spinning wheels, wherein the gyro spinning wheels are rotated in spin motion by the spin drive motor and the cone assembly is rotated in precession motion by the precession drive motor. The device further comprises of a gyro cover operatively connected to support the plurality of magnetized gyro spinning wheels and comprising a slot, wherein the spin motion and the precession motion causes leaking of ether through the slot. The ether can also be leak through a guide duct operatively connected to the slot to generate the desired torque and thrust.

    Status of Patent: Worldwide Patent Pending

    Assistance given by IIPRD

  • Conducted Commercial Evaluation of the Product/Patent
  • Complete Patent Protection Through Khurana & Khurana
  • Executing the complete Licensing Exercise Worldover by Identifying, Negotiating and Closing the deal with one or more Potential Licensees

  • Antibiotic Fixed Dose Combination


    Fixed Dose Combination of two antibiotics: cefepime hydrochloride (a cephalosporin) and amikacin sulphate (an aminoglycoside) administered as a single product. The product is developed to overcome multi bacterial, complicated hospital acquired ICU infections particularly in deadly diseases like Nosocomial Pneumonia and Febrile Neutropenia

    Status of Patent: Granted in India, South Africa, and South Korea. Patent Pending in multiple other geographies

    Assistance given by IIPRD

  • Conducted Commercial Evaluation of the Product/Patent
  • Executing the complete Licensing project in South African Market by Identifying, Negotiating and Closing the deal with a Potential Licensee

  • Machine for Manufacturing Welded Metal Trellis


    The invention relates to a machine for the production of a continuous strip of wire mesh using a single flexible metal wire which is fed to the machine continuously. The mesh is formed by repeating the same pattern with the metal wire in one plane, each pattern being stacked on the preceding pattern with a constant pitch offset in the axial direction of production.

    Status of Patent:Patent Granted in Multiple geographies

    Assistance given by IIPRD

  • Conducted Commercial Evaluation of the Patent for the Indian Market

  • Delamination of Laminated Packaging Refuse


    The invention relates to a process for recovery of useful constituents from multilayer laminated fragments arising as waste from industrial packaging manufacture. It relates more particularly to recovery of polyethylene plastic and aluminium foil from multilayered, laminated fragments containing these materials. According to the process disclosed, the delamination of the laminated constituents of the packaging waste fragments is carried out by keeping the fragments immersed in nitric acid of 50 - 70 % concentration at ambient temperature for 3 to 6 hour duration. The aluminium foils get fully separated from the plastics and the constituents remain in a submerged/floating condition. The delaminated constituents are removed from the nitric acid bath and allowed to pass through a series of bath for washing and separation of the materials. The fragments of separated aluminium foils and separated plastic are centrifuged to dryness and then allowed a sun bath for total drying. The separated fragments of aluminium foils can be used for producing aluminium ingots or sold as such. Similarly the separated fragments of plastic can be used for producing recycled plastic granules or sold as such.

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    Status of Patent: Granted in India (IN 209755), Europe, Canada, and Israel. PCT Application No. PCT/IN2001/000218

    Assistance given by IIPRD

  • Conducted Freedom to Operate Search
  • Conducted Patent Valuation
  • Identification of Potential Licensees and Close to completing first round of negotiations with a Licensee
  • Ventilation Box
    The present invention relates to a ventilation board, an insulating board, a ventilation system, and articles and architectural applications comprising said ventilation board and a method of manufacturing the ventilation board. The said ventilation board comprises a layer (11) provided with a first aperture (5); an adjacent layer provided (13) with a second aperture (7), the first and second apertures being located relative to each other such that they are non-aligned and are substantially without overlap; and a passageway (9) interconnecting the first and second apertures thereby permitting the passage of fluid therebetween.; Therefore, the carton comprising said ventilation board when used for fast food packaging provides sufficient ventilation of the carton so that water condensed from food vapors does not run on to the food in the carton, and sufficient insulation so that the food in the carton is kept warm.

    Status of Patent: Patent Pending in India, United States, Europe, and other major geographies. PCT Application No. PCT/IN2005/000184

    Assistance given by IIPRD
  • Conducted Freedom to Operate Search
  • Conducted Patent Valuation
  • Smart Fabric
    This invention is smart textile fabric which is adapted to be applied as a common comfortable fabric, in all weather conditions and seasons all over the globe. It effectively maintains a uniform temperature around human/animal body on which fabric is worn, irrespective of the environmental temperature variations by applying a shape memory alloy (SMA) actuation principle. This invention provides a self actuated smart textile, which does not require external energy in the form of electrical / electronic power / system or any other mode of assisted energy, for its function.

    Status of Patent: Patent Pending in India. Indian Application No. 793/CHE/2009

    Assistance given by IIPRD
  • Conducted Commercial Evaluation
  • System for Secured Storage and Usage of Digital Assets
    This system in general relates to a communication system for secured communication, storage and display of digital assets / contents and in particular to a compact system, which may be portable, having a detachably attached means such as monitor/screen/display, whereby said system serves as a medium for communication, storage and display of digital assets / contents in a secured way, preventing piracy and duplication. This system uses satellite communication in a unique manner, applying laser rays and other advances in satellite technology, and also is adapted to have internet linkage. This device provides a unique technology for receipt and usage of digital assets / contents. In the devise is further used Screen or monitor or page can be removed from the hardware device and rolled in and kept aside. Screen can be made from Micro-Electro Mechanical Systems (MEMS), which however is accessible only by the storage means of a specifically mapped device.

    Status of Patent: Patent Pending in India.

    Assistance given by IIPRD
  • Conducted Commercial Evaluation
  • Transferring Television Settings to Configure Televisions
    A system and method for transferring television configuration settings from a primary television having preset television settings to automatically configure a secondary television is descried. A user can connect a removable memory device to the primary television. The primary television can extract television configuration settings from the memory of the television and export the settings to the removable memory device. The television configuration settings are stored in the removable memory device as a file having one or more file formats wherein the file is readable and editable and therefore the file can be prioritized based on user preference. The removable memory device can be connected to the secondary television. The secondary television can extract the television configuration settings from the removable memory device and import them to the memory of the secondary television such that the secondary television is automatically configured with the television configuration settings of the primary television.

    Status of Patent: Patent Pending in India. Indian Application No. 211/DEL/2008

    Assistance given by IIPRD
  • Patent Application Drafting and Filing through Khurana & Khurana, Advocates and IP Attorneys
  • Conducted Commercial Evaluation
  • Conducted Patent Valuation and Freedom to Operate Study
  • Biodegradable Polymer Composition
    The invention disclosed in this application relates to a novel biodegradable additive polymer composition useful for the preparation of biodegradable plastic products which comprises of a mixture of (i) a polymer selected from Polyethylene, polypropylene, poly styrene, poly vinyl chloride or a mixture thereof (ii) Cellulose ( iii) Amides ( iv) nutrients selected from Blue green algae and / or Yeast and (v) Water. This composition can be mixed with a virgin polymer to get a master polymer. The master batch composition may be mixed with a virgin polymer, which is useful for preparing products which are biodegradable.

    Status of Patent: Patent Pending in India, United States, Europe, and other major geographies. PCT Application No. PCT/IN2007/000165

    Assistance given by IIPRD
  • Patent Valuation
  • Clever-Texting Mechanism for Touch-Typable Devices
    The present invention relates to systems and methods for entering text input in touch-typable devices such as mobile phones using an unambiguous keypad typing scheme for faster typing on limited keypads using a movable keymask and an optimized dynamic key assignment.

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    Status of Patent: Patent Pending: PCT Application (Application No. PCT/IN2009/000715) and Indian Application (Application No. 2873/DEL/2008)Filed

    Assistance given by IIPRD
  • Patent Application Drafting and Filing through Khurana & Khurana, Advocates and IP Attorneys
  • Lime Stone and Navasar Based Multi-Purpose Composition
    The present invention relates to a Lime Stone (Calcium Carbonate)and Navasar (Ammonium Chloride)Based Multi-Purpose Composition.

    Status of Patent: Patent Application Filed and Pending In India: Indian Application No. 1348/MUM/2007

    Assistance given by IIPRD
  • Commercial Evaluation and Cost/Feasibility Analysis Study
  • Commercializing the Invention to Potential Licensees
  • In-House Cricket
    The in-house cricket, more particularly indoor cricket includes a board, which contains 101 boxes with a view of pitch and score board can be folded into two, three or four columns. Further, the present invention comprises a ball having ten sides showing numbers of runs from zero to four and six, no ball and wide ball.

    Status of Patent: Indian Patent Granted (Patent No. IN207044)and Expired. Copyright granted for the Game.

    Assistance given by IIPRD
  • Commercializing the Game to Major Game Players in India
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