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Polyisoprenylated Benzophenones As Inhibitors Of Histone Acetyltransferases

Invention relates to Polyisoprenylated benzophenones and their isomers as inhibitors of histone acetyltransferases. These compounds are useful as biological switching molecules for evaluating the role of p300 and PCAF in cellular functions and also may be useful as new chemical entities for the development of anticancer drugs.

Patent Application Number: 7402706

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Stereo-Selective Preparation Of 3-Hydroxy-3-(2-Thienyl) Propanenitrile

Technology relates to a Chemoenzymatic process for the stereoselective preparation of both enantiomers of 3-hydroxy-3-(2-thienyl) propanenitrile, which are optically pure intermediates for the synthesis of both enantiomers of duloxetine in high enantiomeric excess.

 

Patent Number: 7045341, Granted Indian and EP Patent.

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Lutein From Oleoresin

Invention relates to a Process for isolating, purifying and formulating commercial grade lutein paste from oleoresin. Process comprises dissolving oleoresin in alcohol to obtain xanthophylls esters , hydrolyzing with base, quenching, drying ester layer and finally mixing the obtained lutein crystals with non-water soluble fractions to obtain stable lutein paste. Lutein thus prepared can be made stable during storage without use of chemical additives and also available at viable prices.

Patent Application Number:7179930

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Chemoenzymatic Process For Stereoselective Preparation Of (R)-GABOB And Carnitine

Technology relates to a chemoenzymatic process for Stereoselective preparation of (R)-GABOB and Carnitine comprising tosylating 3,4-dihydroxybutanenitrile, resoluting racemic 3-hydroxy-4-tosyloxybutanenitrile and coverting the racemate to (R)-GABOB and Carnitine.

 

Patent Application Number:7816119

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Preparation Process Of Chromium Dioxide And Other Oxides

Invention relates to a process for preparing chromium dioxide and other oxides of chromium. Hard sintered chromium oxide can be obtained without introducing any detectable impurity phase and the obtained chromium oxides and composites have shown significant negative magnetoresistance near room temperature. Chromium oxides have application in magnetic recording application.

Patent Application Number: 7276226

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Chemoenzymatic Process For Stereoselective Preparation Of (R)-GABOB

Technology relates to a chemo enzymatic process for the stereo selective preparation of both enantiomers of 3-hydroxy-4-trityloxy butanenitrile and their effective application in the preparation of (R)-GABOB through an enantioconvergent process comprising transesterifying 3-hydroxy-4-trityloxybutanenitrile, transforming optically pure 3-acetyloxy-4-trityloxybutanenitrile to (R)-GABOB and transforming 3-hydroxy-4-trityloxybutanenitrile to (R)-GABOB.

Patent Application Number: 7374926 , Granted EP, Indian and JP patent.

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